Effects of a single dose of fluoride on calcium metabolism.

M J Larsen, F Melsen, L Mosekilde, M S Christensen
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引用次数: 5

Abstract

Fluoride 27 mg was given perorally to 14 subjects. It was found that the serum fluoride concentration increased followed by a decrease to normal levels during 24 h. Serum concentrations of calcium and phosphate decreased initially whereas those of serum immunoreactive parathyroid hormone increased. After 24 h the measured quantities were within normal limits. The results are discussed with reference to mineralization of hard tissues and to fluoride treatment of osteoporotic patients.

单剂量氟化物对钙代谢的影响。
14名受试者口服氟化物27毫克。血清氟化物浓度在24 h内先升高后降至正常水平,钙、磷酸盐浓度先降低,甲状旁腺免疫反应性激素浓度升高。24h后测得的量在正常范围内。并结合硬组织矿化和骨质疏松患者的氟化物治疗进行了讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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