Daniel C. Hatton, Reva Tankle, Thomas Lanthorn, Merle E. Meyer
{"title":"Serotonin and tonic immobility in the rabbit","authors":"Daniel C. Hatton, Reva Tankle, Thomas Lanthorn, Merle E. Meyer","doi":"10.1016/S0091-6773(78)92956-5","DOIUrl":null,"url":null,"abstract":"<div><p>Wallnau and Gallup (<span>L. B. Wallnau and G. G. Gallup, 1977, <em>Biobehav. Rev.</em> <strong>1</strong>, 35–43</span>) recently proposed a serotonergic midbrain raphé model of tonic immobility (TI), wherein there is an inverse relationship between raphé activity and the duration of TI. In part, this model was based on the results of central and peripheral injections of serotonin in chickens which increase and decrease TI, respectively. In rats, centrally administered serotonin depresses raphé firing (<span>G. K. Aghajanian, 1972, <em>Fed. Proc.</em> <strong>31</strong>, 91–96</span>) while peripherally administered serotonin potentiates raphé firing (<span>S. Mosko and B. L. Jacobs, 1974, <em>Brain Res.</em> <strong>79</strong>, 315–320</span>). The present investigation examined the effect of central and peripheral injections of serotonin on the duration of TI in rabbits. The results were not in agreement with Wallnau and Gallup's predictions. The data suggest that serotonergic influences on TI vary across species.</p></div>","PeriodicalId":75577,"journal":{"name":"Behavioral biology","volume":"24 1","pages":"Pages 97-100"},"PeriodicalIF":0.0000,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0091-6773(78)92956-5","citationCount":"14","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0091677378929565","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 14
Abstract
Wallnau and Gallup (L. B. Wallnau and G. G. Gallup, 1977, Biobehav. Rev.1, 35–43) recently proposed a serotonergic midbrain raphé model of tonic immobility (TI), wherein there is an inverse relationship between raphé activity and the duration of TI. In part, this model was based on the results of central and peripheral injections of serotonin in chickens which increase and decrease TI, respectively. In rats, centrally administered serotonin depresses raphé firing (G. K. Aghajanian, 1972, Fed. Proc.31, 91–96) while peripherally administered serotonin potentiates raphé firing (S. Mosko and B. L. Jacobs, 1974, Brain Res.79, 315–320). The present investigation examined the effect of central and peripheral injections of serotonin on the duration of TI in rabbits. The results were not in agreement with Wallnau and Gallup's predictions. The data suggest that serotonergic influences on TI vary across species.
沃尔瑙和盖洛普(l.b.沃尔瑙和g.g.盖洛普，1977，生物行为学。Rev. 1,35 - 43)最近提出了一种色氨酸能中脑紧张性静止(TI)的raph模型，其中raph活性与TI持续时间呈反比关系。在一定程度上，该模型是基于中央和外周注射血清素的结果，分别增加和降低了TI。在大鼠实验中，中央给药血清素抑制脑神经放电(G. K. Aghajanian, 1972, Fed. Proc. 31,91 - 96)，而周围给药血清素增强脑神经放电(S. Mosko and B. L. Jacobs, 1974, Brain Res. 79, 315-320)。本研究考察了中央和外周注射血清素对家兔TI持续时间的影响。结果与沃尔瑙和盖洛普的预测并不一致。数据表明，血清素对TI的影响因物种而异。
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