The tubular reabsorption of phosphate in sickle-cell nephropathy.

P E De Jong, L T de Jong-van Den Berg, L W Statius van Eps
{"title":"The tubular reabsorption of phosphate in sickle-cell nephropathy.","authors":"P E De Jong,&nbsp;L T de Jong-van Den Berg,&nbsp;L W Statius van Eps","doi":"10.1042/cs0550429","DOIUrl":null,"url":null,"abstract":"<p><p>1. In a series of patients with sickle-cell anaemia, serum phosphate and magnesium concentrations were elevated. Serum calcium concentrations were normal. Urinary excretion of calcium was decreased. 2. The maximum tubular reabsorption of phosphate per litre of glomerular filtrate (TmP/GFR) was significantly increased in these patients. 3. The increase in phosphate reabsorption explains the elevated serum phosphate observed in these patients.</p>","PeriodicalId":10356,"journal":{"name":"Clinical science and molecular medicine","volume":"55 5","pages":"429-34"},"PeriodicalIF":0.0000,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs0550429","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical science and molecular medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1042/cs0550429","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18

Abstract

1. In a series of patients with sickle-cell anaemia, serum phosphate and magnesium concentrations were elevated. Serum calcium concentrations were normal. Urinary excretion of calcium was decreased. 2. The maximum tubular reabsorption of phosphate per litre of glomerular filtrate (TmP/GFR) was significantly increased in these patients. 3. The increase in phosphate reabsorption explains the elevated serum phosphate observed in these patients.

镰状细胞肾病中磷酸盐的小管重吸收。
1. 在一系列镰状细胞性贫血患者中,血清磷酸盐和镁浓度升高。血钙浓度正常。尿钙排泄减少。2. 在这些患者中,每升肾小球滤液中磷酸盐的最大小管重吸收(TmP/GFR)显著增加。3.磷酸盐重吸收的增加解释了在这些患者中观察到的血清磷酸盐升高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信