Immunosenescence in Autoimmune Related to Periodontal Disease : A Review Article

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by the development of autoantibodies and immune complexes associated with a variety of clinical manifestations and tissue damage. SLE is the production of reactive antibodies against the body’s own cells. SLE is multifactorial and most likely involves complex interactions between genetic, environmental, and hormonal factors. There is an aging process in immune cells due to changes in the innate and adaptive immune system compartments. This phenomenon is known as Immunosenescence, also occurs on autoimmune. One of the characteristics of elderly people is their inability to respond to vaccines and infections properly.