Prescribing trend of treating malaria patients by public and private healthcare facilities in Lahore

Nayab Goher, Farhan Hameed Khaliq, Muhammad Waleed Yousaf
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Abstract

Malaria is an infectious disease caused by parasites of the Plasmodium genus. It is one of the major causes of morbidity and mortality worldwide. The World Health Organization (WHO) has recommended artemisinin combination therapy (ACT) to manage malaria among children and adults. However, chloroquine as monotherapy and ACT are commonly prescribed in treating malaria in Pakistan's healthcare delivery system. Therefore, this study assessed the prescribing trends for treating malaria patients in public and private healthcare facilities. Moreover, the study also determined the number of drugs prescribed per prescription by physicians and consultants. This descriptive study was conducted for six months in Lahore's major public and private healthcare facilities. A purposive sampling technique was employed to review 300 malaria patients' prescriptions accessed from the hospital records. Descriptive statistics and the chi-square test were used to achieve the study's objectives. The study showed that most malaria prescriptions were from both public (64.67%) and private healthcare facilities (42.67%) and comprised a dual-drug regimen involving antimalarials, antibiotics, antipyretics, or their combinations. There was a significant difference (p = 0.002) in the prescription trend between public and private healthcare facilities regarding the number of drugs prescribed for treating malaria. Moreover, prescriptions from private healthcare facilities mainly contained antimalarial drugs (58.59%) and antibiotics (17.60%), while most prescriptions from public healthcare facilities contained antipyretics and other drugs (60.67%) (p = 0.001). Most of the consultants prescribed two (66.67%) or three drugs (33.33%), while the prescribing trends of physicians ranged between one and four, which was also statistically significantly different (p = 0.001). In addition, most prescriptions from public healthcare facilities were rationally prescribed (68%). On the other hand, most prescriptions from private healthcare facilities were rational (54%) and semirational (42%). The rationality of prescriptions by public and private healthcare facilities was also significantly different (p = 0.001). Public healthcare facilities were found to exhibit more rational prescribing trends for managing malaria compared to private healthcare facilities, with a focus on prescribing an optimal number of drugs per prescription and a lower usage of antimalarial and antibiotic medications.
拉合尔公立和私立医疗机构治疗疟疾患者的处方趋势
疟疾是一种由疟原虫属寄生虫引起的传染病。它是全世界发病率和死亡率的主要原因之一。世界卫生组织(世卫组织)建议采用青蒿素联合疗法来管理儿童和成人的疟疾。然而,在巴基斯坦的卫生保健服务系统中,氯喹作为单一疗法和以青蒿素为基础的联合疗法通常用于治疗疟疾。因此,本研究评估了公立和私立医疗机构治疗疟疾患者的处方趋势。此外,该研究还确定了医生和咨询师开出的每张处方的药物数量。这项描述性研究在拉合尔的主要公共和私人医疗机构进行了为期六个月的研究。采用有目的抽样技术审查了从医院记录中获得的300名疟疾患者的处方。采用描述性统计和卡方检验来实现研究目标。研究表明,大多数疟疾处方来自公立(64.67%)和私立卫生保健机构(42.67%),包括双药方案,包括抗疟药、抗生素、退烧药或其组合。在为治疗疟疾开出的药物数量方面,公立和私立医疗机构之间的处方趋势有显著差异(p = 0.002)。私立医疗机构处方以抗疟药(58.59%)和抗生素(17.60%)为主,公立医疗机构处方以退烧药和其他药物(60.67%)为主(p = 0.001)。咨询医师处方2种(66.67%)或3种(33.33%)药物较多,内科医师处方趋势在1 ~ 4种之间,差异也有统计学意义(p = 0.001)。此外,大多数公立医疗机构的处方是合理的(68%)。另一方面,大多数私人医疗机构的处方是理性的(54%)和半国家级的(42%)。公立和私立医疗机构处方的合理性也存在显著差异(p = 0.001)。研究发现,与私营医疗机构相比,公共医疗机构在管理疟疾方面表现出更合理的开处方趋势,重点是每张处方开出最佳数量的药物,减少抗疟药和抗生素药物的使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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