Preliminary Experimental Characterization of Gelatin-Based Tissue-Mimicking Materials for Realistic Breast Phantoms aimed at Microwave Applications

S. Di Meo, S. Morganti, L. Pasotti, M. Conti, M. Pasian, G. Matrone
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引用次数: 3

Abstract

Breast cancer is the most aggressive and common cause of death among women around the world, and an early diagnosis is fundamental to increase the survival chances. Microwave and mm-wave imaging systems have been recently proposed as a possible technique for cancer detection, on the grounds of the different dielectric permittivity between healthy and neoplastic tissues. To support the experimental development of such systems, phantoms able to mimic the different dielectric permittivity are required. In addition, the possibility to provide, at the same time, mechanical properties similar to those of real tissues would be beneficial to deliver phantoms as realistic as possible. In this paper, two simple and easy-to-produce mixtures able to mimic the dielectric properties of neoplastic breast tissue are presented; their dielectric properties are compared to the ones derived from human neoplastic ex-vivo samples and their mechanical properties are tested. In particular, two different percentages of gelling material are used and both the dielectric and mechanical material properties are measured, demonstrating the possibility to tune the Young’s module of the samples.
用于微波应用的真实乳房模型的明胶基组织模拟材料的初步实验表征
乳腺癌是世界各地妇女最具侵略性和最常见的死亡原因,早期诊断对于增加生存机会至关重要。基于健康组织和肿瘤组织之间介电常数的不同,微波和毫米波成像系统最近被提出作为一种可能的癌症检测技术。为了支持这种系统的实验发展,需要能够模拟不同介电常数的幻影。此外,在提供与真实组织相似的机械性能的同时,这种可能性将有助于使幻影尽可能逼真。本文介绍了两种简单且易于制作的能够模拟乳腺肿瘤组织介电特性的混合物;将其介电性能与人肿瘤离体样品的介电性能进行了比较,并对其力学性能进行了测试。特别地,使用了两种不同百分比的胶凝材料,并测量了介电和机械材料的性能,证明了调整样品的杨氏模块的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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