Lemuru Fish (Sardinella Lemuru) Oil effects on Body Weight of Wistar Rats Induced by Trans Fatty Acids

Jurnal Kesehatan Prima Pub Date : 2022-02-01 DOI:10.32807/jkp.v16i1.792

Abdurrahman Ali, A. Adi, S. Adiningsih

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引用次数: 1

Abstract

The content of EPA and DHA in lemuru fish oil can be used to prevent obesity risk factors. This study aims to determine the effect of purified lemuru fish oil on the weight of Wistar rats induced by trans fatty acids. This research is an experimental study using a randomized block design with a post test only control group. The research sample was 30 male Wistar rats aged two to three months, grouped into two control groups (K) which were given standard feed (K0) and those given standard feed after two weeks of trans fatty acid induction (K1) and three treatment groups (P). ) with lemuru fish oil intervention as much as 0.34 ml (P1), 0.67 ml (P2), and 1.34 ml (P3). The induction material was 2.3 g of liquid margarine, containing 3.8% trans fatty acids. The intervention material was lemuru fish oil from the purification process containing 18.05% EPA and 9.37% DHA. Induction of margarine for two weeks made the body weight of the rats increased by 27.90% (P2) compared to the control (K0) 16.06%. After the intervention period of lemuru fish oil for three weeks, the weight of the treatment group P1 (18.53%), P2 (14.74%), and P3 (13.19%) was lower than the control group K0 (22.79%) and K1 (25.31%).

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狐猴鱼油对反式脂肪酸诱导Wistar大鼠体重的影响

狐猴鱼油中EPA和DHA的含量可以用来预防肥胖的危险因素。本研究旨在研究纯化狐猴鱼油对反式脂肪酸诱导的Wistar大鼠体重的影响。本研究采用随机区组设计，仅设后测对照组。以2 ~ 3月龄雄性Wistar大鼠30只为研究对象，分为对照组(K)和对照组(K)，分别饲喂标准饲料(K0)和经2周反式脂肪酸诱导(K1)后饲喂标准饲料(K)和3个治疗组(P)。狐猴鱼油干预量分别为0.34 ml (P1)、0.67 ml (P2)和1.34 ml (P3)。诱导材料为2.3 g液体人造黄油，含3.8%反式脂肪酸。干预材料为提纯后的狐猴鱼油，EPA含量为18.05%，DHA含量为9.37%。人造黄油诱导2周后，大鼠体重较对照组(K0)增加27.90% (P2)，对照组(K0)增加16.06%。狐猴鱼油干预期3周后，治疗组P1(18.53%)、P2(14.74%)和P3(13.19%)的体重均低于对照组K0(22.79%)和K1(25.31%)。

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Jurnal Kesehatan Prima

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