Differential Refractometric Platform for Reliable Biosensing based on Long-period Gratings and Molecular Imprinting

Abstract

A new (bio)sensing platform based on differential refractometric measurements was developed. The sensing scheme is based on the combination LPFGs/MIP/NIP, involving a dual channel system for real-time compensation of non-specific interactions. The correction system improves the sensor behavior by reducing the response to interferents by 30%.