Ultrastructural changes in mouse peritoneal exudate cells during infection with Toxoplasma gondii.

Abstract

Infections of mouse peritoneal exudate cells with trophozoites of Toxoplasma gondii (BK strain) were studied by means of electron microscopy. After i.p. injection of Toxoplasma-trophozoites macrophages, lymphocytes, neutrophilic and eosinophilic granulocytes migrate into the peritoneal cavity of mice. All these cells can be parasitized by T. gondii. Multiplication of phagocytosed trophozoites is not inhibited, but obviously the infected cells favour their growth.