Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.)

Elsye Gunawan, Aris A.L. Toruan, Rusnaeni Rusnaeni, F. E. Appa
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Abstract

The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants
蛇木植物的抗凝活性(Strychnos lucida R.Br)
蛇木植物(Strychnos lucida)的茎在经验上被用作疟疾药物,缓解发烧,治疗胃痛,痔疮,风湿病,中风症状,并改善血液循环。单宁是蛇木茎的次生代谢产物之一,它含有稀释血液的没食子酸化合物。本研究的目的是测定蛇木茎乙醇提取物对血型A、B、AB、o的抗凝活性。提取方法为浸渍法,抗凝剂检测采用改良Lee-White法和血涂片法,数据分析采用描述性分析。采用Lee-White修饰法对血型样品进行目视不凝血。血液涂片法的抗凝血活性表明,蛇皮提取物在显微镜下可以阻止血块的存在,这些血块可以与不相关的血细胞观察到,完整且彼此分离。关键词:露珠;李·怀特修改;血涂片;抗凝血剂
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