Fully Automated Interpretable Breast Ultrasound Assisted Diagnosis System

Daniel X M Wang, Yongzhen Wang, Yingchen Wang, Longzhong Liu, Jia-wei Li, Qinghua Huang
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Abstract

Breast cancer is one of the most vulnerable malignant tumors for women in the world, which seriously threatens women's life and health. Fortunately, through timely screening, early breast cancer patients have a high cure rate, which is expected to reach complete recovery. Ultrasound imaging is a screening technology for breast cancer that is superior to the pathological judgment of puncture. It is less harmful to the patient and has the advantages of easy operation and real-time, so it is currently widely used. In order to alleviate the shortage of medical resources and improve screening efficiency, the technology of the breast cancer computer-aided diagnosis system came into being. This paper proposes a new and interpretable fully automated breast ultrasound computer-aided diagnosis method, which can automatically extract the corresponding medical features used by doctors after inputting an ultrasound image and infer the final diagnosis result through the knowledge association between these features. First, the input ultrasound image is read intelligently, similar to the reading process of ultrasound doctors. The diagnostic system extracts medical features useful for diagnosis from the ultrasound image. The second step is associating the extracted features with the known breast benign and malignant diagnosis knowledge graph and finally determining the benign and malignant tumor in this ultrasound image through the correlation relationship in the knowledge graph which is presented as a knowledge tensor. The experimental results show that the fully automated breast ultrasound CAD system proposed in this paper can realize the tradeoff between interpretability and accuracy.
全自动可解释乳腺超声辅助诊断系统
乳腺癌是世界上妇女最易患的恶性肿瘤之一,严重威胁妇女的生命和健康。幸运的是,通过及时筛查,早期乳腺癌患者的治愈率很高,有望达到完全康复。超声成像是一种优于穿刺病理判断的乳腺癌筛查技术。它对患者的伤害较小,具有操作方便、实时性好等优点,目前得到了广泛的应用。为了缓解医疗资源短缺,提高筛查效率,乳腺癌计算机辅助诊断系统技术应运而生。本文提出了一种新的可解释的全自动乳腺超声计算机辅助诊断方法,该方法在输入超声图像后,自动提取医生使用的相应医学特征,并通过这些特征之间的知识关联推断出最终的诊断结果。首先,智能读取输入的超声图像,类似于超声医生的读取过程。该诊断系统从超声图像中提取对诊断有用的医学特征。第二步是将提取的特征与已知的乳腺良恶性诊断知识图进行关联,最后通过知识图中的相关关系确定该超声图像中的良恶性肿瘤,知识图以知识张量的形式表示。实验结果表明,本文提出的全自动乳腺超声CAD系统能够实现可解释性与准确性的平衡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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