Retrospective Evaluation of 112 Patients with Brucellosis Diagnosis in Siirt

Abstract

Aim: In this study, we aimed to evaluate epidemiological, clinical, laboratory findings and treatment regimens of brucellosis cases. Material and Method: 112 patients diagnosed with brucellosis in the polyclinics of Siirt State Hospital between March 2018 and June 2019 were retrospectively analyzed. Epidemiological, clinical, laboratory findings and treatment regimens of brucellosis cases were evaluated. Results: It was determined that 38.4% of 112 cases included in the study were male and 61.6% were female. The average age was determined as 38.1 (18–76) years. 56% of the patients applied from villages, 19% of applied from districts and 37% of applied from the city. The most frequent complaints of the patients at the first admission were body pain, joint pain, weakness, fever, headache, and low back pain. In physical examination, arthritis, arthralgia, myalgia, hepatomegaly, splenomegaly and lymphade-nopathy were detected in 30.1%, 78.8%, 84.1%, 9.7%, 8% and 2.7% of cases, respectively. In the laboratory examination of the patients; Leukopenia, leukocytosis, anemia, and polycythemia were determined in 12.4%, 7.1%, 33.6%, and 2.7% of cases, re-spectively. The Brucella Coombs agglutination test was found to be above 1/320 in 14 cases, 1/640 in 20 cases, 1/280 in 25 cases, 1/2560 in 17 cases and 1/5120 in 36 cases. Elevated liver enzymes were found in 46.9% of patients, sedimentary height was found in 54.9%, and CRP elevation was found in 33.6%. The patients were mainly treated with doxycycline + rifampicin, doxycycline + rifam-picin + ceftriaxone and doxycycline + ceftriaxone. Conclusion: As a result, the findings we obtained from our study show that the incidence of brucellosis is still high in our province of Siirt, where animal husbandry is intensive. In addition, brucellosis should be considered in the differential diagnosis in patients presenting with non-specific complaints such as fever, joint pain, and weakness.