A high-throughput bioinformatics distributed computing platform

Thomas M. Keane, Andrew J. Page, J. McInerney, T. Naughton
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引用次数: 2

Abstract

In the past number of years the demand for high performance computing has greatly increased in the area of bioinformatics. The huge increase in size of many genomic databases has meant that many common tasks in bioinformatics are not possible to complete in a reasonable amount of time on a single processor. Recently distributed computing has emerged as an inexpensive alternative to dedicated parallel computing. We have developed a general-purpose distributed computing platform that is capable of using semi-idle computing resources to simulate a dedicated computing cluster. We have identified the suitability of a number of bioinformatics tasks to distributed computing. We briefly outline and evaluate two distributed bioinformatics programs, DSEARCH and DPRml, which have been developed for our system.
高通量生物信息学分布式计算平台
在过去的几年里,生物信息学领域对高性能计算的需求大大增加。许多基因组数据库规模的巨大增长意味着生物信息学中的许多常见任务不可能在单个处理器上在合理的时间内完成。最近,分布式计算已经成为专用并行计算的廉价替代品。我们开发了一个通用的分布式计算平台,能够使用半空闲的计算资源来模拟一个专用的计算集群。我们已经确定了许多生物信息学任务对分布式计算的适用性。我们简要地概述和评价了为我们的系统开发的两个分布式生物信息学程序,DSEARCH和DPRml。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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