Effects of Dietary Fish Oil and/or Sake Lees on the Concentration of Serum Lipids and Anxiety Behavior in Rats

Japanese Journal of Complementary and Alternative Medicine Pub Date : 2020-05-26 DOI:10.1625/jcam.17.43

Yasue Hososyamada, Masako Yamada

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Abstract

Effects of Dietary Fish Oil and/or Sake Lees on the Concentration of Serum Lipids and Anxiety Behavior in Rats Yasue HOSOSYAMADA, Masako YAMADA Department of Nutrition, Faculty of Health Care Sciences, Chiba Prefectural University of Health Sciences Department of Food and Nutrition, Faculty of Contemporary Human Life and Science, Tokyo Kasei Gakuin University Objectives: We studied the effects of fish oil and sake lees combined with a high fat diet in rats, and assessed serum lipids concentrations and anxiety behavior. Methods: Male Sprague-Dawley rats aged 5 weeks were fed a diet containing the Soybean oil (Control), Soybean oil + Sake lees (S), Fish oil (FO) or FO + Sake lees (FO+S) for 18days. The control diet contained a soybean oil component. It was measured the concentrations of serum lipids and anxiety behavior. Results: The concentration of serum cholesterol were significantly lower in the FO+S group than in the Control group. The concentration of serum triglyceride and free fatty acids were significantly lower in the FO group and the FO+S group than in the Control group. In anxiety behavior, the stay time in the zone of open arm were significantly higher in the S group than in the

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鱼油和/或清酒对大鼠血脂浓度和焦虑行为的影响

膳食中鱼油和/或清酒对大鼠血脂浓度和焦虑行为的影响我们研究了鱼油和清酒与高脂饮食结合对大鼠的影响，并评估了血脂浓度和焦虑行为。方法:5周龄雄性Sprague-Dawley大鼠分别饲喂大豆油(对照)、大豆油+清酒渣(S)、鱼油(FO)或鱼油+清酒渣(FO+S)饲粮18d。对照组饮食中含有大豆油成分。测定血清脂质浓度和焦虑行为。结果:鱼油+S组血清胆固醇浓度明显低于对照组。鱼油组和鱼油+S组血清甘油三酯和游离脂肪酸浓度显著低于对照组。在焦虑行为方面，S组在张开手臂区停留时间显著高于S组

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Japanese Journal of Complementary and Alternative Medicine

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