Access to Infertility Care and Utilization of a Regional Fertility Preservation Program for Cancer Patients

Jennifer Chae-Kim, Robert A. Roman, Tongil Kim, L. Gavrilova-Jordan
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Abstract

Background. Fertility preservation (FP) prior to gonadotoxic cancer treatment is underutilized in the United States (US) due to limited access to care. Objective. We aimed to determine the utilization of a regional FP program in an underserved region in the Southeast US. Methods. We performed an institutional review board-approved retrospective cohort study of patients enrolled in the FP program at an academic tertiary medical center from 2014 to 2018. Results. Sixtynine reproductive age patients were enrolled in the FP program, including 29 men and 40 women between 20 and 49 years of age. Cancer diagnoses among the enrolled patients included hematologic (n = 34), breast (n = 14), testicular (n = 11), reproductive tract (n = 7), and gastrointestinal (n = 3) malignancies. Patients with reproductive tract malignancies were found to have approximately 9.7 times greater odds of proceeding with FP than patients with hematologic malignancies (P < .05). Conclusion. Utilization of a regional FP program should be considered to increase access to care to this critical resource for patients desiring future family building. Patients with hematologic malignancy may face unique barriers to FP.
获得不孕症护理和利用区域生育保护计划的癌症患者
背景。在美国,由于获得护理的机会有限,在促性腺毒性癌症治疗之前的生育能力保存(FP)未得到充分利用。目标。我们的目的是确定一个区域计划生育计划的利用率在美国东南部服务不足的地区。方法。我们进行了一项机构审查委员会批准的回顾性队列研究,研究对象是2014年至2018年在一家学术三级医疗中心参加计划生育项目的患者。结果。69名育龄患者参加了计划生育项目,包括29名男性和40名女性,年龄在20至49岁之间。在入选的患者中,癌症诊断包括血液学(n = 34)、乳腺(n = 14)、睾丸(n = 11)、生殖道(n = 7)和胃肠道(n = 3)恶性肿瘤。生殖道恶性肿瘤患者比血液学恶性肿瘤患者进行FP治疗的几率约为9.7倍(P < 0.05)。结论。应考虑利用区域计划生育计划,为希望未来建立家庭的患者增加对这一关键资源的护理机会。血液恶性肿瘤患者可能面临独特的FP障碍。
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