A Case Report : Diabetic Ketoacidosis in patient with type 1 Diabetes Mellitus with Complication Septic Shock and AKI Stage III on HD Triggered by Perianal Abscess

Muhammad Ikhsan Kartawinata, Yusni Puspita
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Abstract

ABSTRACT Introduction. Diabetic ketoacidosis (DKA) is an acute, life-threatening complication in diabetes mellitus. Infection is a common precipitating cause of diabetic ketoacidosis (DKA) in known diabetic patient, and diabetic ketoacidosis (DKA) often presents as the first symptom of an undiagnosed diabetes. diabetic ketoacidosis (DKA) is diagnosed with combination of hyperglicaemia, acidosis metabolic and ketonuria. Case Presentation. A 27 years old male patient, admitted to Intensive Care Unit with decrease level of consciousness (GCS 3), he was intubated and present with respiratory distress, metabolic acidosis, high glucose level, ketonuria with renal failure as a target organ. Patient known has perianal abscess as a triggered of diabetic ketoacidosis (DKA), turn into septic shock and underwent debridement surgery to source control the infection. The patient was treated in intensive care unit for 9 days, and sent to ward with GCS 15 an no sequelae of organ failure. The treatment of diabetic ketoacidosis (DKA) should include correcting the often substantial hypovolemia, the hyperglycemia, electrolyte imbalance and the triggering factor of diabetic ketoacidosis (DKA). Conclusion. Prompt surgical intervention, antibacterial therapy, rapid restoration of glycemic control are crucial to prevent mortality in diabetes mellitus patients complicated with abscess.
1型糖尿病酮症酸中毒合并脓毒性休克合并急性肾衰III期,并发肛周脓肿
摘要介绍。糖尿病酮症酸中毒(DKA)是一种危及生命的急性糖尿病并发症。感染是已知糖尿病患者糖尿病酮症酸中毒(DKA)的常见诱因,糖尿病酮症酸中毒(DKA)常作为未确诊糖尿病的首发症状出现。糖尿病酮症酸中毒(DKA)是一种伴有高血糖、代谢性酸中毒和酮症尿的疾病。案例演示。27岁男性患者,因意识水平下降(GCS 3)入住重症监护室,插管后出现呼吸窘迫、代谢性酸中毒、高血糖、酮症尿伴靶器官肾功能衰竭。患者已知肛周脓肿为糖尿病酮症酸中毒(DKA)的诱因,转为感染性休克,行清创手术控制感染源。患者在重症监护室治疗9天,以GCS 15分送入病房,无器官衰竭后遗症。糖尿病酮症酸中毒(DKA)的治疗应包括纠正经常严重的低血容量、高血糖、电解质失衡和糖尿病酮症酸中毒(DKA)的触发因素。结论。及时手术干预、抗菌药物治疗、迅速恢复血糖控制是预防糖尿病合并脓肿患者死亡的关键。
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