ANTIMICROBIAL RESISTANCE OF PATHOGENS OF HEALTHCARE-ASSOCIATED INFECTIONS IN SURGERY AND INTENSIVE CARE UNITS

Abstract

OBJECTIVE. To determine resistance to antibiotics of the pathogens of healthcare-associated infections (HAIs) in surgery and intensive care units in Kyiv hospitals. MATERIALS AND METHODS. The investigation included the analysis of 6159 strains from patients with clinical symptoms HAIs. The identification and antimicrobial susceptibility of cultures were determined, using automated microbiology analyzer Vitek 2 Compact (BioMerieux, France). Susceptibility to antibiotics was determined using AST cards (BioMerieux, France). Some antimicrobial susceptibility test used Kirby – Bauer antibiotic testing. Interpretative criteria were those suggested by the CLSI (USA). RESULTS. The leading agents are E.coli, S.aureus, S.epidermidis, P.aeruginosa, Enterobacter in surgical departments, and Klebsiella, Acinetobacter spp., P.aeruginosa and Enterobacter in departments of intensive care. Multiple resistant hospital cultures are shared in surgical as well as in the departments of intensive care. Its susceptibility to antibiotics was given. CONCLUSIONS. HAIs remain an important cause of morbidity in surgery and intensive care units. Antimicrobial resistance among these and other clinically important pathogens is an increasing problem. The clinical should choose antimicrobial drug in accordance with the local bacterial resistance characteristics for reduce the production of drug resistance and improve the effect of anti-infection treatment possibly.