Formation of Self-organized Structures in Drying Droplets: a Promising Analytical Tool for Homeopathy Basic Research

M. Kokornaczyk, Sandra Würtenberger, L. Betti, G. Trebbi, Mario Castelán, Carlos Acuña, S. Baumgartner
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Abstract

The droplet evaporation method (DEM) is based on the evaporation-induced pattern formation in droplets and is applied mainly for diagnosis [1]. Here, we present a series of experiments performed by our team showing DEMs potential also for homeopathy basic research, in particular, for the investigation of (i) low potencies, (ii) low potency complexes (physical model), and (iii) the action of high potencies (plant-based model). DEM differentiated significantly between Luffa, Baptisia, Echinacea, and Spongia until 4x [2]. Furthermore, the patterns varied in function of the number of succussion strokes (0, 10, or 100) applied during potentization [3]. The performance of chaotic succussions vs. laminar flow vs. slight mixing during the potentization of Viscum album quercus 3x influenced the DEM patterns; the chaotic succussions reduced, whereas laminar flow enhanced the patterns complexity vs. the unsuccussed control. The addition of Mercurius bijodatus 9x to Luffa 4x changed significantly the DEM patterns, even if the material quantity present in the 9x potency lied far beyond that of ultrapure water. Leakages obtained by placing healthy or damaged wheat-seeds into Arsenicum album 45x or Zincum metallicum 30c vs. water created significantly different DEM structures [4, 5]. The damaged seeds put into the potency created structures characterized by a higher complexity than those obtained from damaged seeds put into control water. Furthermore, the potency action seemed to correlate positively with the number of succussion strokes applied during potentization, as could be shown by means of DEM patterns and germination rate using the same wheat-seed model [6]. In all our studies, the pattern evaluation was computerized or based on deep-learning algorithms and the robustness of the experimental system was checked by means of systematic control experiments. DEM together with other similar methods has also been reviewed by our team for what concerns the application in homeopathy basic research [7].  
干燥液滴中自组织结构的形成:顺势疗法基础研究的一种有前途的分析工具
液滴蒸发法(DEM)基于液滴中蒸发诱导的模式形成,主要用于诊断[1]。在这里,我们展示了我们团队进行的一系列实验,显示了dem在顺势疗法基础研究中的潜力,特别是在(i)低效、(ii)低效复合物(物理模型)和(iii)高效作用(植物模型)的研究中。DEM在Luffa、Baptisia、Echinacea和Spongia之间存在显著差异,直到4x[2]。此外,在电位增强过程中,这种模式会随着连续触击次数(0,10或100次)的变化而变化[3]。在槲皮3次强化过程中,混沌流、层流和轻微混合的表现影响了DEM模式;与不间断控制相比,混沌干扰降低,层流增强了模式的复杂性。在丝瓜液4x中添加墨丘利斯9x后,尽管9x效力中存在的物质数量远远超过超纯水,但显著改变了DEM模式。将健康或受损的小麦种子放入Arsenicum album 45x或zinc metallum 30c和water中获得的泄漏产生了显著不同的DEM结构[4,5]。与放入对照水中的受损种子相比,放入效价中的受损种子所产生的结构具有更高的复杂性。此外,效价作用似乎与在增强过程中施加的震荡次数呈正相关,这可以通过使用相同的小麦种子模型的DEM模式和发芽率来证明[6]。在我们所有的研究中,模式评估都是计算机化的或基于深度学习算法的,并通过系统控制实验来检验实验系统的鲁棒性。我们的团队也对DEM和其他类似方法在顺势疗法基础研究中的应用进行了回顾[7]。
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