Impedance spectroscopy systems: Review and an all-digital adaptive IIR filtering approach

Abstract

Impedance spectroscopy is a low-cost sensing technique that is generating considerable interest in wearable and implantable biomedical applications since it can be efficiently integrated on a single microchip. In this paper, the fundamental characteristics of the most well-known system architectures are presented, and a more robust and hardware-efficient solution is proposed. An all-digital implementation based on adaptive filtering is used for identifying the impedance parameters of a sample-under-test. The coefficients of an infinite-impulse-response (IIR) filter are tuned by an adaptive algorithm based on pseudo-linear regression and output-error formulation. A three-level pseudorandom noise generator with a concave power spectral density is employed without deteriorating the nominal performance. Proof-of-concept has been verified with behavioral simulations.