MEMS based Flow Cytometer with Instrumentation System for Detection of Micro Particles for Health Care Applications

Abstract

Detection, counting and analysis of biological cells is an important aspect in health care systems for which a microfluidic impedance flow cytometers have been globally accepted to measure the dielectric parameters of micro cells/particles at high speed. The cells/particles are allowed through a micro-channel having planar bottom electrodes. DC voltage is applied and output of the microfluidic device is recorded through necessary signal conditioning circuit and data acquisition system. In the present work, polystyrene particles of 10μm diameter flowing in medium of phosphate buffered saline having conductivity of 0.156Sm−1 are analyzed to successfully demonstrate the efficacy of the flow cytometer.