Drug Data Mining of Sini Decoction Based on Ancient and Modern Medical Cases

Abstract

Objective: To excavate the internal drug use rules by analyzing the related medical cases of Sini Decoction in ancient and modern society, it can provide reference for the reasonably use of Sini Decoction in clinic. Methods: Using data mining technology, collecting ancient and modern medical cases, standardizing the collected drug data, establishing a database of medical cases related to Sini Decoction, and analyzing its internal drug use rules. Results: A total of 370 medical cases of Sini Decoction were retrieved, among which the high-frequency drugs included aconite, dried ginger, licorice, poria, etc., and the high-frequency drug types included warm medicine, tonic medicine, epidemic medicine, and diuretic dampness medicine, etc., 21 potential drug combinations were found, among which the high-frequency drug combinations included dried ginger → aconite, licorice → aconite, poria → aconite, etc. Conclusion: When Sini Decoction was used to treat clinical diseases, attention should be paid to the combination of tonic medicine and warm medicine, so as to achieve the effect of back to Yang to rescue and supplementing both Yin and Yang. The epidemic medicine, dampness medicine and qi-regulating medicine are used as auxiliary, so as to achieve the purpose of treating diseases.