Biological treatment for rheumatoid arthritis: a review of the main approved monoclonal antibodies

Abstract

Introduction Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that has a high destructive potential throughout its progression. The disease evolution generates significant social and economic costs. 1–3 This is a multifactorial and systemic disease of unknown etiology, which can mainly affect the joints, evolving with joint destruction and deformity, often becoming incapacitating. 4,5 Abstract