Analysis of Regional Deformation of the Heart's Left Ventricle Using Curvature Values with Hotelling T2 Metric

Abstract

This paper presents a robust method of local deformation analysis of the heart's left ventricle (LV) aimed at specifying the affected area. Our method is based on regional curvature variation calculation using the Hotelling T2 two samples difference metric. It has been validated with real data obtained from myocardial scintigraphy imaging techniques of 44 patients. For each patient we extract 3D surfaces representing the anatomical structures of interest, namely the endocardium and epicardium at stress. In order to progress to a regional analysis, we carried out, for each patient, a division into 17 regions according to the AHA standard. Experimental results demonstrate the great robustness and efficiency of our method.