Autologous Osteoblast-cell Therapy in Orthodontics and Implantology: A Single-center Experience of Nine Patients

Dilip Deshpande
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Abstract

Resorption of bone post tooth extraction is an established fact. In addition to this, pneumatization of maxillary sinuses further reduced the available bone and space for dental implant restoration. Traumatic loss of bone and bone loss due to cystic disease adds another dimension to clinical presentation and management. Various modalities have been used for bone replacement or restoration and are well documented. Here, we present a case series of nine patients, wherein a novel autologous cultured osteoblast cell product was used for bone augmentation in different clinical settings, with a quite satisfactory long-term outcome. We recommend the use of this revolutionary approach in rightly selected patients for permanent bone regeneration in the treatment of various oral and maxillofacial defects.
自体成骨细胞治疗正畸和种植:9例患者的单中心经验
拔牙后骨的吸收是一个既定的事实。除此之外,上颌窦的气化进一步减少了种植体修复的可用骨和空间。外伤性骨丢失和囊性疾病引起的骨丢失增加了临床表现和治疗的另一个维度。各种方式已被用于骨置换或修复,并有充分的记录。在这里,我们提出了9例患者的病例系列,其中一种新型的自体培养成骨细胞产品在不同的临床环境中用于骨增强,具有相当满意的长期结果。我们推荐在正确选择的患者中使用这种革命性的方法进行永久性骨再生治疗各种口腔和颌面缺损。
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