LESI NERVUS OKULOMOTOR INVOLVED PUPIL ET CAUSA ANEURISMA PADA PASIEN DENGAN STROKE SUBARACHNOID HEMORRHAGIC DAN SYSTEMIC LUPUS ERITHEMATOSUS

I. K. Aryawan, A. Triningrat, Made Paramita Wijayanti, I. Indrayani, Pande Ketut Kurniari
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Abstract

Introduction: Oculomotor nerve palsy is an pathological condition caused by microvascular injury, head injury, compression due to neoplasm or aneurysm, and also oculomotor nerve palsy can be caused by autoimmune prosses. Peripheral neuropathy is one of the clinical manifestations in patient with SLE, Oculomotor nerve palsy is one type of cranial neuropathy seen with SLE patient. Patient with SLE have a higher risk of serebrovascular event than general population. Case Illustration: Female 34 years old complained drop of the eyelid on the left eye and double vision when see with both eyes since 1 mounth before examination. Patient with history of headace and diagnosed with SLE since 2006 with regular treatment. From the examination, pupil anisocor, on the right eye pupil was 3 mm in diameter with positif direct and indirect reflex. On the left eye pupil was 6 mm with negative direct and indirect reflex. Extraocular movement on the left eye was limited except abduction movement.  CT-Scan examination shows bilateral subarachnoid hemorrhage and from CT-Angiography shows dilatation of the left siphon carotid artery. Patient was diagnosed with oculomotor nerve palsy involving pupil caused by aneurysm with SAH and SLE. Discussion: Oculomotor nerve palsy mostly caused by aneurysm compression in posterior communicating artery (PCoA) and internal carotid artery (ICA). Cerebrovascular imaging, MRA and CTAngiography, can showing the aneurysm and its location. Risk of cerebrovascular event increased in patient with SLE than general population. Management patient with oculomotor nerve palsy with SLE nowadays is with pulse dose corticosteroid. Conclusion: SLE with oculomotor nerve palsy will increase risk of cerebrovascular event. Key Words : Oulomotor Nerve Palsy, Subarachnoid Hemorrhage, Systemic Lupus Erithematosus
导论:动眼神经麻痹是一种由微血管损伤、头部损伤、肿瘤或动脉瘤压迫引起的病理状态,也可由自身免疫过程引起。周围神经病变是SLE患者的临床表现之一,动眼神经麻痹是SLE患者常见的一种颅神经病变。SLE患者发生血管事件的风险高于一般人群。病例说明:女性,34岁,自检查前1个月起,主诉左眼眼睑下垂,双眼视重。患者有头痛病史,2006年以来诊断为SLE,定期治疗。检查结果显示,右眼瞳孔直径3mm,直接反射和间接反射阳性。左眼瞳孔6mm,直接反射和间接反射均为阴性。除外展外,左眼眼外活动受限。ct扫描显示双侧蛛网膜下腔出血,ct血管造影显示左侧虹吸颈动脉扩张。患者被诊断为伴SAH和SLE的动脉瘤引起的动眼神经麻痹及瞳孔。讨论:动眼神经麻痹多因动脉瘤压迫后交通动脉(PCoA)和颈内动脉(ICA)所致。脑血管成像,MRA和ctangography,可以显示动脉瘤及其位置。SLE患者发生脑血管事件的风险高于一般人群。目前对SLE动眼神经麻痹患者的治疗是脉冲剂量皮质类固醇。结论:SLE合并动眼神经麻痹可增加脑血管事件发生的风险。关键词:运动神经麻痹,蛛网膜下腔出血,系统性红斑狼疮
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