Examination of Three Distinct Dosages of Dexmedetomidine for Counteraction of Postspinal Sedation Shivering in Transurethral Resection of Prostate (TURP) Medical Procedure

Dr. Md Rezaul Islam, Dr. Mofizul Karim, D. A. Haque
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Abstract

Background: The ideal portion of dexmedetomidine for shivering control with the most un-hemodynamic disturbances is still under research. Postanesthetic shivering (PAS) is an unsavory and possibly serious difficulty. Not very many investigations have been finished in regards to the ideal compelling portion of dexmedetomidine for the counteraction of postspinal anesthesia (SA) shivering. Accordingly, we expected to look at and assess three distinct portions of intravenous dexmedetomidine and to explore the ideal portion of dexmedetomidine that successfully forestalls shivering in patients going through transurethral resection of the prostate (TURP). Materials and Methods: In this randomized, twofold visually impaired, planned study, 135 patients of the American Society of Anesthesiologists I and II booked for elective TURP under SA were selected. Patients were haphazardly apportioned into one of the three gatherings getting dexmedetomidine: Group P: 0.5 μg/kg, Group Q: 0.75 μg/kg, and Group R: 1.0 μg/kg. The essential result of the review was intraoperative rate of shivering. The optional results, like hemodynamic boundaries. Results: Shivering score of various gatherings uncovered measurably huge lower occurrence and seriousness of shivering in Group Q and Group R when contrasted with Group P(P = 0.0395). Occurrences of sickne, bradycardia, and hypotension were more in Group R when contrasted with Group P and Group Q. Axillary temperature and sedation scores were equivalent among various gatherings (P > 0.05). Conclusion: Dexmedetomidine in the dose of 0.75 μg/kg furnishes sufficient antishivering impact with added advantage of sedation and less hemodynamic disturbance.
三种不同剂量右美托咪定对经尿道前列腺电切术(TURP)中脊髓后镇静寒颤的对抗作用的研究
背景:右美托咪定用于控制大多数非血流动力学紊乱的颤抖的理想剂量仍在研究中。后审美颤抖(PAS)是一个令人讨厌的,可能严重的困难。关于右美托咪定对脊髓后麻醉(SA)寒战的理想抑制作用的研究并不多。因此,我们期望观察和评估静脉注射右美托咪定的三个不同部分,并探索右美托咪定的理想部分,成功地预防经尿道前列腺切除术(TURP)患者的颤抖。材料和方法:在这项随机的、双视力障碍的计划研究中,选择了135名美国麻醉医师协会I和II的患者,他们在SA下预定了选择性TURP。随机分为三组:P组:0.5 μg/kg, Q组:0.75 μg/kg, R组:1.0 μg/kg。回顾的主要结果是术中颤抖率。可选结果,如血流动力学边界。结果:各聚会寒战评分显示,Q组和R组寒战发生率和严重程度均显著低于P组(P = 0.0395)。与P组和q组相比,R组患病、心动过缓、低血压的发生率更高。腋窝温度和镇静评分各组间相当(P > 0.05)。结论:0.75 μg/kg右美托咪定具有良好的抗寒战作用,且具有镇静作用和血流动力学干扰小的优点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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