Heparinized catheters for long-term intraarterial infusion of 5-fluorouracil in liver metastases.

U Tylén, L Forsberg, T Owman
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Abstract

A heparinized catheter was used for the regional infusion of 5-fluorouracil in seven patients with liver metastases. The hepatic artery was catheterized from the left brachial artery. The period of treatment varied from one to 13 weeks. Pull-out angiograms, obtained after eight catheterizations, revealed complete occlusion of the brachial artery in five and partial occlusion in three, although no patient had ischemic symptoms in the hand. Thus, heparinization of the catheter did not prevent thrombosis during long-term infusion therapy.

肝转移患者长期动脉输注5-氟尿嘧啶的肝素化导管。
采用肝素化导管局部输注5-氟尿嘧啶治疗7例肝转移患者。肝动脉从左肱动脉导管入管。治疗时间从1周到13周不等。8例导管置入后获得的拉出血管造影显示,5例肱动脉完全闭塞,3例部分闭塞,但没有患者出现手部缺血症状。因此,在长期输注治疗期间,导管的肝素化并不能预防血栓形成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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