Chunghau Lee, S. Blay, A. Mooers, Ambuj K. Singh, Todd H. Oakley
{"title":"CoMET: A Mesquite package for comparing models of continuous character evolution on phylogenies","authors":"Chunghau Lee, S. Blay, A. Mooers, Ambuj K. Singh, Todd H. Oakley","doi":"10.1177/117693430600200022","DOIUrl":null,"url":null,"abstract":"Continuously varying traits such as body size or gene expression level evolve during the history of species or gene lineages. To test hypotheses about the evolution of such traits, the maximum likelihood (ML) method is often used. Here we introduce CoMET (Continuous-character Model Evaluation and Testing), which is module for Mesquite that automates likelihood computations for nine different models offrait evolution. Due to its few restrictions on input data, CoMET is applicable to testing a wide range of character evolution hypotheses. The CoMET homepage, which links to freely available software and more detailed usage instructions, is located at http://www.lifesci.ucsb.edu/eemb/labs/oakley/software/comet.htm.","PeriodicalId":136690,"journal":{"name":"Evolutionary Bioinformatics Online","volume":"34 3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"37","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Evolutionary Bioinformatics Online","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/117693430600200022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 37
Abstract
Continuously varying traits such as body size or gene expression level evolve during the history of species or gene lineages. To test hypotheses about the evolution of such traits, the maximum likelihood (ML) method is often used. Here we introduce CoMET (Continuous-character Model Evaluation and Testing), which is module for Mesquite that automates likelihood computations for nine different models offrait evolution. Due to its few restrictions on input data, CoMET is applicable to testing a wide range of character evolution hypotheses. The CoMET homepage, which links to freely available software and more detailed usage instructions, is located at http://www.lifesci.ucsb.edu/eemb/labs/oakley/software/comet.htm.
不断变化的特征,如体型或基因表达水平在物种或基因谱系的历史中进化。为了检验关于这些特征进化的假设,通常使用最大似然(ML)方法。在这里,我们介绍CoMET (Continuous-character Model Evaluation and Testing),这是Mesquite的一个模块,可以自动计算9种不同模型的似然演化。由于对输入数据的限制很少,CoMET适用于测试广泛的字符进化假设。CoMET的主页链接到免费软件和更详细的使用说明,网址是http://www.lifesci.ucsb.edu/eemb/labs/oakley/software/comet.htm。