Spillover Effects of Drug Safety Warnings on Health Behavior

N. M. Daysal, C. Orsini
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Abstract

We examine the impact of new medical information on drug safety on preventive health behavior. We exploit the release of the findings of the Women's Health Initiative Study (WHIS) – the largest randomized controlled trial of women's health – which demonstrated in 2002 that long-term Hormone Replacement Therapy increases the risk of heart attacks, stroke, blood clots and breast cancer among healthy post-menopausal women. Because hormone replacement is a therapy exclusive to women, we estimate the spillover effects of the WHIS findings on health behavior by means of a difference-in-differences methodology using men of similar ages as the control group. Using data from the Behavioral Risk Factor Surveillance System for 1998-2007, we find statistically significant small negative spillovers on post-menopausal women's likelihood of having an annual checkup and choice of a healthy diet, as proxied by daily fruit consumption. Our results also indicate that the observed spillover effects of drug safety on health behavior were entirely driven by the less educated. These findings suggest that policies aimed at raising awareness on the safety of medications may have unintended spillover effects on health behavior and that these spillovers may contribute to the existing health disparities by education.
药物安全警示对健康行为的溢出效应
我们研究了药物安全对预防健康行为的新医学信息的影响。我们利用了妇女健康倡议研究(WHIS)——最大的妇女健康随机对照试验——的研究结果,该研究在2002年表明,长期激素替代疗法增加了健康绝经后妇女患心脏病、中风、血栓和乳腺癌的风险。由于激素替代是一种专门针对女性的治疗方法,我们使用年龄相近的男性作为对照组,通过差异中差异的方法来估计WHIS研究结果对健康行为的溢出效应。利用1998-2007年行为风险因素监测系统的数据,我们发现,在统计上,绝经后妇女每年进行体检和选择健康饮食的可能性存在显著的小负面溢出效应,如每天食用水果所代表的那样。我们的研究结果还表明,观察到的药物安全对健康行为的溢出效应完全由受教育程度较低的人驱动。这些发现表明,旨在提高对药物安全性认识的政策可能会对健康行为产生意想不到的溢出效应,这些溢出效应可能会通过教育加剧现有的健康差距。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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