Experimental study of biological effect on canine stomach in vitro by Nd:YAP laser

Abstract

Objective: To evaluate the biological effect of Nd:YAP laser in different power and irradiation time on canine stomach in vitro. Methods: The canine stomach in vitro was irradiated by Nd:YAP laser with different power and irradiation time. The damage with naked eye, micro and ultramicro structure was observed. Results: The thermal coagulation effect is mostly and the ablation effect is subordinate on biological effect of Nd:YAP laser on canine stomach in vitro. Thermal coagulation and denaturalization time of whole stratum in pathology is 10W, 5s; 20W, 4s; 30W, 2s; 40~60W, 1s. Conclusions: Safety dose of laser beam on canine stomach in vitro is 10W, time less than 5s; 20W, time less than 4s; 30W, time less than 2s. The ablation and thermal coagulation effects of Nd:YAP laser on canine stomach in vitro is positive correlative with power and time.