Action Mechanisms of Antirheumatic Herbal Medicines

Nima Nakisa, M. Rahbardar
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引用次数: 3

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory and debilitating joint disorder that causes severe impairment and reduces the quality of life. The available synthetic medicines used as standard therapy for RA have numerous side effects that can compromise their therapeutic outcomes. Thus, the demand for alternative and complementary medicines is increasing. A search of English articles in PubMed, Scopus, Google Scholar, and Web of Science databases was carried out on probable mechanisms of action of herbs with the antirheumatic property. Herbal medicines stated in folk medicine face acceptance concerns by the medical community because of the lack of scientific documents regarding their physio-pharmacological mechanisms. This chapter aims to review the possible antirheumatic effects of various herbs, including Rosmarinus officinalis L., Curcuma longa, and Crocus sativus, their related mechanisms, and preclinical applications, in order to recall the therapeutic properties of herbal medicine. However, more clinical trials are required to confirm the safety and efficacy of these antirheumatic herbal medicines.
抗风湿中药的作用机制
类风湿性关节炎(RA)是一种慢性炎症性和衰弱性关节疾病,可导致严重损伤并降低生活质量。现有的用于类风湿性关节炎标准治疗的合成药物有许多副作用,可能影响其治疗效果。因此,对替代和补充药物的需求正在增加。在PubMed, Scopus, Google Scholar和Web of Science数据库中检索英文文章,对具有抗风湿特性的草药的可能作用机制进行了搜索。由于缺乏关于其生理药理学机制的科学文献,民间医学中所述的草药面临医学界的接受问题。本章旨在综述迷迭香、姜黄、藏红花等多种中草药可能的抗风湿作用、相关机制及临床前应用,以回顾中草药的治疗特性。然而,需要更多的临床试验来证实这些抗风湿病草药的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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