Effects of Avocado Yoghurt, Three Beans Cookie, and Tiger Nut Galsu Drink on Fibroblasts (Hs68) and Keratinocytes (HaCaT)

Seung-yong Park, Eunkyung Jung, N. Joo, Hyun-Soo Shin, Ji-Sun Shin, Da-Bin Myoung, Kyung-Tae Lee
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Abstract

The present study aimed to investigate the effects of skin care foods on the synthesis of pro-collagen type I C peptide and suppression of matrix metalloproteinase (MMP)-1 secretion through an in vitro study using fibroblasts (Hs68 cells) and keratinocytes (HaCaT cells). Among the three skin care foods developed in this study, three beans cookie and avocado yoghurt influenced the production of pro-collagen type I C peptide and suppressed MMP-1 secretion; however, tiger nut Galsu drink did not exhibit these effects. All skin care foods, including three beans cookie and plain yoghurt (50 μg/mL, p<0.001) influenced the suppression of MMP-1 in addition to other commercially available breast milk production support foods examined, such as Heath Heather (50 μg/mL, p<0.001), Happy Mama (50 μ g/mL, p<0.01), BioLys (50 μg/mL, p<0.001), Enfamama (25 μg/mL, p<0.0001), and Pregnagen (25 μg/mL, p<0.001). Avocado fruit yoghurt (25 μg/mL, p<0.05), avocado fruit jam yoghurt (50 μg/mL, p<0.01), Enfamama (100 μg/mL, p<0.05), and Pregnagen (100 μg/mL, p<0.05) influenced the production of pro-collagen type I C peptide and suppressed MMP-1 secretion. This result indicates that only avocado jam yoghurt significantly influenced both the prevention of skin keratinization and acceleration of recovery of skin fibrous structure. Therefore, avocado is a favorable ingredient for nutrition-balanced dietary foods or an essential ingredient in products for revitalization of human skin.
牛油果酸奶、三豆饼干和虎坚果饮料对成纤维细胞(Hs68)和角质形成细胞(HaCaT)的影响
本研究旨在通过体外成纤维细胞(Hs68细胞)和角质形成细胞(HaCaT细胞)研究护肤食品对前胶原I型C肽合成和基质金属蛋白酶(MMP)-1分泌的影响。在本研究开发的三种护肤食品中,三豆饼干和鳄梨酸奶影响了前胶原I型C肽的产生,抑制了MMP-1的分泌;然而,虎坚果加素饮料没有表现出这些效果。所有皮肤护理食品,包括三豆饼干和纯酸奶(50 μg/mL, p<0.001)都影响MMP-1的抑制,此外还有其他市售的母乳生产支持食品,如Heath Heather (50 μg/mL, p<0.001)、Happy Mama (50 μg/mL, p<0.01)、BioLys (50 μg/mL, p<0.001)、Enfamama (25 μg/mL, p<0.0001)和Pregnagen (25 μg/mL, p<0.001)。牛油果酸奶(25 μg/mL, p<0.05)、牛油果果酱酸奶(50 μg/mL, p<0.01)、Enfamama酸奶(100 μg/mL, p<0.05)和Pregnagen酸奶(100 μg/mL, p<0.05)影响了前胶原I型C肽的产生,抑制了MMP-1的分泌。结果表明,只有牛油果果酱酸奶对预防皮肤角化和加速皮肤纤维结构恢复有显著影响。因此,牛油果是营养均衡饮食的有利成分,也是振兴人体皮肤产品的必需成分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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