AEROBIC VAGINITIS (AV): DISEASE BURDEN, BACTERIOLOGICAL PROFILE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN IN WESTERN MAHARASHTRA

Deepa Devhare
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Abstract

Vaginitis is a very common and recurrent infection in reproductive age group especially worrisome in pregnant females. If it is misdiagnosed, left untreated or wrongly treated can lead to serious complications. With this background present study was conducted to determine the prevalence, bacteriological profile and antimicrobial susceptibility of the pathogens causing aerobic vaginitis. Study was conducted over a period of 1year in which 241 vaginal swabs were processed for aerobic culture and gram stain. The organisms were identified and antimicrobial susceptibility was performed by Vitek 2 compact system. Out of 241 samples processed 37(15.4%) showed bacterial growth. S. aureus (40.5%), GBS (13.5%), E. coli (13.5%) and K. pneumoniae (13.5%) were the common pathogens isolated. Gram positive organisms showed highest sensitivity to Vancomycin and Linezolid. All gramnegative bacteria were sensitive to Imipenem and Meropenem. This study recommends the laboratory-based diagnosis of each clinically suspected case of vaginitis for appropriate management of patient. Addition of antibacterial agent in traditional empirical antifungal therapy for vaginitis is need of hour
马哈拉施特拉邦西部需氧性阴道炎(av):疾病负担、细菌学概况和抗菌药物敏感性模式
阴道炎是育龄人群中一种非常常见的反复感染,尤其在孕妇中令人担忧。如果误诊,不及时治疗或错误治疗可导致严重的并发症。在此背景下,本研究旨在确定引起需氧性阴道炎的病原菌的患病率、细菌学特征和抗菌药物敏感性。研究进行了1年,其中241个阴道拭子进行了有氧培养和革兰氏染色。采用Vitek 2紧凑系统进行菌群鉴定和药敏试验。在处理的241个样品中,有37个(15.4%)显示细菌生长。常见病原菌分别为金黄色葡萄球菌(40.5%)、GBS(13.5%)、大肠杆菌(13.5%)和肺炎克雷伯菌(13.5%)。革兰氏阳性菌对万古霉素和利奈唑胺敏感性最高。革兰氏阴性菌对亚胺培南和美罗培南均敏感。本研究建议对每个临床疑似阴道炎病例进行实验室诊断,以便对患者进行适当的治疗。传统经验性阴道炎抗真菌治疗中加入抗菌剂需要较长时间
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