Human friendly control system of alveolar CO/sub 2/-concentration based on adaptive control theory

K. Takahara, H. Wakamatsu
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引用次数: 2

Abstract

The purpose of the present study is to construct a basic experimental system for automatic control of alveolar CO/sub 2/-concentration during controlled and assisted respiration. This system consists of a newly developed computer-controlled respirator and its controlling devices. In the present study, ventilation rate and alveolar CO/sub 2/-concentration are regarded as the input and output of the controlled object, respectively. The automatic control system of alveolar CO/sub 2/-concentration is designed using an adaptive pole-placement method. The proposed system is applied to clinically basic control experiments of alveolar CO/sub 2/-concentration both in controlled and assisted respiration. Furthermore, physiological experiments are made on healthy subjects during light exercise in order to ascertain the robustness of the system. Thus, the proposed system is confirmed to be useful for the control of alveolar CO/sub 2/-concentration taking into account characteristic differences of the respiratory regulation system due to chronic change and individuality.
基于自适应控制理论的人类肺泡CO/sub - 2浓度友好控制系统
本研究的目的是构建一个控制和辅助呼吸时肺泡CO/sub 2/-浓度自动控制的基础实验系统。该系统由新研制的计算机控制呼吸器及其控制装置组成。本研究将通气量和肺泡CO/sub 2/-浓度分别作为被控对象的输入和输出。采用自适应极点放置法设计了肺泡CO/sub 2/-浓度自动控制系统。本系统应用于控制呼吸和辅助呼吸下肺泡CO/sub 2/-浓度的临床基础对照实验。此外,为了验证该系统的鲁棒性,还对健康受试者进行了轻度运动时的生理实验。因此,考虑到呼吸调节系统因慢性变化和个体化而存在的特征差异,该系统被证实可用于控制肺泡CO/sub 2/-浓度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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