Pseudoangiomatous stromal hyperplasia causing massive unilateral breast enlargement—a case report

Abstract

Pseudoangiomatous stromal hyperplasia (PASH) is an uncommon mesenchymal benign breast neoplasm (1). It was first studied by Vuitch et al. in 1986 in 9 patients who presented with palpable, grossly circumscribed, nonhaemorrhagic breast masses (2). On histological examination, the masses were composed of mammary s tromal proliferations with complex anastomosing channels lined with slender spindle cells stimulating vascular channels (3). Therefore, the histological appearance resembles, without constituting, an angiomatous proliferation (3). Vuitch et al. highlighted the importance of distinguishing this Case Report