Role of External Ventricular Drainage (EVD) in Treating Spontaneous Intraventricular Haemorrhage

Md. Mahfuzur Rahman, Md. Shamiul Alam Siddique, Md Shafiqul Islam, A. Sarker, Sukriti Das, Fazle Elahy, M. Z. Rahman
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Abstract

Background: There is no consensus in the literature on the effects of the development of hydrocephalus on survival and disability after intracerebral haemorrhage (ICH) and the benefits of external ventricular drainage (EVD). This study is planned to describe the role of external ventricular drainage in treating patients of spontaneous, either primary or secondary, intraventricular haemorrhage with hydrocephalus.Material & Methods:A hospital based prospective interventional study was conducted in the Department of Neurosurgery of Dhaka Medical College Hospital, which is a tertiary level hospital, from April 2016 to September 2017.Total 42 patients of spontaneous intraventricular haemorrhage, either primary or secondary, with hydrocephalus were selected for this study. All the collected data were entered into IBM SPSS software, Version 24. For statistical analysis, paired t-test to compare the preoperative GCS with postoperative GCS at 24 hours was done.Results:Among 42 patients, age range was 26-75 years with the mean age 65.2 ± 10.87 years. Male were 26 (61.9%) and female were 16 (38.1%). Male-Female ratio was 1.625:1. No patient needed conversion of EVD into VP shunt. EVD drain became blocked in 5 cases which were managed accordingly. 5 patients developed ventriculitis among which 2 patients died and rest 3 improved with antibiotics.Conclusions:The results of present study shows that EVD has a good role in the treatment of spontaneous IVH with hydrocephalus when ICH volume is low (<30ml) and modified Graeb Score is low (≤10 found in this in this study. Preoperative higher GCS or initial improvement in GCS or initial improvement in GCS at 24 hours positively correlates with Glasgow outcome scale which is an indication of good function outcome.
脑室外引流术治疗自发性脑室内出血的作用
背景:关于脑积水的发生对脑出血(ICH)后生存和残疾的影响以及脑室外引流(EVD)的益处,文献尚未达成共识。本研究计划描述脑室外引流在治疗自发性脑室内出血合并脑积水患者中的作用,无论是原发性还是继发性。材料与方法:2016年4月至2017年9月在三级医院达卡医学院附属医院神经外科进行了一项基于医院的前瞻性介入研究。本研究共选择42例原发性或继发性脑积水自发性脑室内出血患者。所有收集到的数据输入IBM SPSS软件,版本24。统计学分析采用配对t检验比较术前与术后24小时GCS。结果:42例患者年龄26 ~ 75岁,平均年龄65.2±10.87岁。男性26例(61.9%),女性16例(38.1%)。男女比例为1.625:1。没有患者需要将EVD转化为VP分流术。5例EVD引流管堵塞,并进行了相应处理。5例发生脑室炎,2例死亡,其余3例经抗生素治疗好转。结论:本研究结果表明,EVD在脑积水体积低(<30ml)、修正Graeb评分低(本研究发现≤10)时对自发性IVH合并脑积水有较好的治疗作用。术前GCS较高或GCS初步改善或24小时GCS初步改善与格拉斯哥结局评分呈正相关,这是良好功能结局的指示。
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