Automatic Left Ventricle Segmentation Algorithm using K-mean Clustering and Graph Searching on Cardiac MRI

Hyun-Wu Jo, Hae-Yeoun Lee
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Abstract

To prevent cardiac diseases, quantifying cardiac function is important in routine clinical practice by analyzing blood volume and ejection fraction. These works have been manually performed and hence it requires computational costs and varies depending on the operator. In this paper, an automatic left ventricle segmentation algorithm is presented to segment left ventricle on cardiac magnetic resonance images. After coil sensitivity of MRI images is compensated, a K-mean clustering scheme is applied to segment blood area. A graph searching scheme is employed to correct the segmentation error from coil distortions and noises. Using cardiac MRI images from 38 subjects, the presented algorithm is performed to calculate blood volume and ejection fraction and compared with those of manual contouring by experts and GE MASS software. Based on the results, the presented algorithm achieves the average accuracy of 6.2mL5.6, 2.9mL3.0 and 2.1%1.5 in diastolic phase, systolic phase and ejection fraction, respectively. Moreover, the presented algorithm minimizes user intervention rates which was critical to automatize algorithms in previous researches.
基于k均值聚类和图搜索的心脏MRI左心室自动分割算法
通过分析血容量和射血分数来量化心功能是预防心脏疾病的重要手段。这些工作都是手工完成的,因此需要计算成本,并且根据操作人员的不同而有所不同。本文提出了一种左心室自动分割算法,对心脏磁共振图像上的左心室进行分割。在补偿MRI图像线圈的灵敏度后,采用k均值聚类方法对血段区域进行聚类。采用图搜索的方法,对线圈畸变和噪声造成的分割误差进行了校正。利用38名受试者的心脏MRI图像,对该算法进行了血容量和射血分数的计算,并与专家和GE MASS软件手工轮廓的计算结果进行了比较。结果表明,该算法在舒张期、收缩期和射血分数的平均准确率分别为6.2mL5.6、2.9mL3.0和2.1%1.5。此外,该算法最大限度地减少了用户干预率,这是以往研究中算法自动化的关键。
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