Carcinoma of the penis: analysis of 192 consecutive cases at the Instituto Nacional de Enfermedades Neoplasicas.

J Pow-Sang, J Ojeda, G Ramirez, L Olivares, V Benavente, L Sanchez
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Abstract

Between 1952 and 1976 192 consecutive cases of penile epidermoid carcinoma were seen at the Instituto Nacional de Enfermedades Neoplascias of Lima, Peru. The mean age when the disease developed was 60.5 years, with a peak incidence between 60 and 64 years (32 patients). No correlation was observed between extensive lesions of the shaft of the penis to high pathological staging. Clinical examination of the inguino-crural nodes is not a good criterion for staging. We wait six weeks after eradication of primary lesion before lymphadenectomy. No correlation exists between grade and pathological stage. When no lymph node was positive, the overall survival rate over five years was 90.69%; when lymph nodes were metastasized there was an overall survival rate over five years of only 9.39 percent. The coefficient of cancer versus noncancer cause of death was 1.25 for pathological stage I, 3.09 for pathological stage II, 4.83 for pathological stage III, and 10.000 for pathological stage IV. Our patients did have advanced disease, as 57.14% of deaths occurred at two years and 25.21% more at five years.

阴茎癌:国家肿瘤研究所连续192例病例分析。
1952年至1976年间,秘鲁利马国立肿瘤研究所连续收治了192例阴茎表皮样癌病例。发病的平均年龄为60.5岁,发病高峰为60 ~ 64岁(32例)。阴茎轴的广泛病变与高病理分期之间没有相关性。临床检查腹股沟-脚淋巴结不是一个很好的分期标准。我们在原发病灶根除后等待6周再行淋巴结切除术。分级与病理分期无相关性。无淋巴结阳性时,5年总生存率为90.69%;当淋巴结转移时,5年的总生存率只有9.39%。病理I期癌症与非癌症死因的系数为1.25,病理II期为3.09,病理III期为4.83,病理IV期为10,000。我们的患者确实有晚期疾病,因为57.14%的死亡发生在2年,25.21%的死亡发生在5年。
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