[Chemotaxis of blood monocytes and polymorphonuclear leukocytes from patients with diabetes mellitus].

Abstract

The chemotaxis of blood monocytes and polymorphonuclear leukocytes was measured in 20 adult patients with diabetes mellitus and 11 normal control subjects. In experiments dealing with monocytes, the diabetics had a chemotaxis value (125+/-10) significantly lower than that of controls (368+/-22); the polymorphonuclear leukocytes chemotaxis value of diabetics (468+/-31) was also lower than normal (1256+/-62). Adding insulin (10 unit/1000 cc) to the diabetes leukocytes suspension significantly increased the value of chemotaxis.