Clinical utility of the erythrocyte sedimentation rate test and haemoglobin electrophoretic patterns among premarital couples in Port Harcourt, Nigeria

Abstract

Background: The erythrocyte sedimentation rate (ESR) is a relatively non-specific test that is often ignored during the diagnosis and monitoring of disease. However, in recent times, the test is often requested alongside haemoglobin electrophoretic pattern as pre marital test. This study was aimed at determining the ESR values among these apparently healthy populations, correlate this parameter with Hb electrophoretic pattern and evaluate its usefulness in modern medicine. Materials and Methods: Standard haemoglobin electrophoresis run with cellulose acetate paper at pH 8.9 and Westergren method for ESR were used in the determinations. Results: The mean ESR value for the males was 12.48±10.0mm/hr while 20.77 ± 18.8 was obtained for the females. There was significant difference between the male and female values (t = 3.94; p 100mm/hr) was observed in the study population. ESR was found to correlate negatively with gender (r = -0.248; p Conclusion: There are no sufficient scientific reasons to support the inclusion of ESR as a premarital test so, this practice should be discouraged. Keywords: Erythrocyte sedimentation rate, haemoglobin electrophoretic pattern, premarital couples