Laparoscopic Heller Myotomy and Dor Fundoplication: Prospective Evaluation of 30 Consecutive Patients

Gholamreza Mohajeri, M. Mahmoudieh, Behrouz Keleidari, M. Shahraki, Elyas Mostafapour, F. Bahrami, S. S. Shahmiri
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Abstract

Background: ProspectivestudiesevaluatingoutcomeoflaparoscopicHellermyotomyandDorfundoplicationforesophagealacha-lasia are less in Asian people. Objectives: This study conducted to evaluate the results of laparoscopic cardiomyotomy and partial fundoplication for achalasia. Patients and Methods: Thirty patients who underwent Heller myotomy for achalasia via laparoscopy in Alzahra hospital Isfahan, Iran were recorded prospectively (2009 - 2013). Median follow-up was 18 months. Symptoms including dysphagia, regurgitation, chest pain and weight loss were recorded before and after operation. Also, previous treatment for achalasia such as endoscopic pneumaticdilatationsandintrasphinctericinjectionof botulinumtoxinorothercomponent,durationof symptomsandduration and complication of operation was recorded. Results: Among 30 patients, there were 13 (43.3%) females and 17 (56.7%) males, and mean age was 40.8 years (range, 20 - 68 years). The operations were finished laparoscopically in all patients. Mean operative time was 137 ± 36.2 minutes. The patients were symptomatic for at least 30 months before referring for surgery. There are some difficulties in dissection in cases who received Ethanolamine or Botholinum Toxin injection as non-surgical treatment before that. Mean hospital stay was 2.45 days. Regurgitation, chest pain and heartburn relieved significantly in median follow up of 18 months, in 100%, 66.6% and 70%, respectively (P < 0.001, P < 0.01 and P < 0.01, respectively). At that time, except for two (6.6%) patients, all other patients had improvement in dysphagia (P < 0.001) .The mucosa in two (6.6%) of patients was perforated on the gastric end of the xylotomy. The perforations were repaired laparoscopically with single suture without postoperative leak. Conclusions: OurstudyshowedthatlaparascopicHelermyotomywithDorfundoplicationresultinsignificantrelief of dysphagia. Overall clinical symptoms indicate improvement in patient functional status during 18-month follow-up. be considered in
腹腔镜Heller肌切开术和Dor扩底术:30例连续患者的前瞻性评价
背景:评价腹腔镜下hellermytomy和dorfundopl术的预后的前瞻性研究在亚洲人群中较少。目的:本研究旨在评价腹腔镜心肌术和部分眼底扩张术治疗贲门失弛缓症的效果。患者与方法:回顾性分析2009 - 2013年在伊朗伊斯法罕Alzahra医院行腹腔镜Heller肌切开术治疗贲门失弛缓症的患者30例。中位随访时间为18个月。手术前后均有吞咽困难、反流、胸痛、体重减轻等症状。同时,记录既往贲门失弛缓症的治疗,如内镜下气动扩张和输注肉毒杆菌毒素或其他成分,症状持续时间,手术持续时间和并发症。结果:30例患者中,女性13例(43.3%),男性17例(56.7%),平均年龄40.8岁(范围20 ~ 68岁)。所有患者均在腹腔镜下完成手术。平均手术时间137±36.2分钟。这些患者在转介手术前至少有30个月的症状。在此之前接受乙醇胺或肉毒毒素注射非手术治疗的病例,解剖困难。平均住院时间2.45天。中位随访18个月时,反流、胸痛、烧心症状明显缓解,分别为100%、66.6%、70% (P < 0.001、P < 0.01、P < 0.01)。除2例(6.6%)患者外,其余患者均有吞咽困难改善(P < 0.001)。2例(6.6%)患者在木骨切开术的胃端出现粘膜穿孔。腹腔镜下单缝线修复穿孔,无术后渗漏。结论:我们的研究表明,腹腔镜下helhelomytomy与dorfundoplplation可显著缓解吞咽困难。在18个月的随访中,总体临床症状表明患者的功能状态有所改善。被认为
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