Potassium Profiling in Hemodialysis

N. Agrawal, Sahil Agrawal, N. Tripathi, M. Segal
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引用次数: 1

Abstract

Cardiac dysrhythmia and sudden death account for a large proportion of cardiac mortality in dialysis patients. Risk factors for sudden death that are specific to dialysis patients include fluid and electrolyte imbalances during hemodialysis, particularly those of potassium. The risk of arrhythmia may be related to changes in serum K+ concentration during dialysis, and thus close attention should be paid to the dialysate K+ concentration and the serum–dialysate concentration gradient. Potassium profiling is a technique where the dialysate K+ concentration is gradually reduced to keep the gradient between blood and dialysate at a non-fluctuating low level. We provide a review of studies that compare constant potassium concentration in dialysate to gradual reduction in dialysate potassium concentration. These studies illustrate that adequate and more gradual potassium removal can be achieved with potassium profiling techniques, while having lower cardiac irritability.
血液透析中的钾谱分析
心律失常和猝死在透析患者心脏死亡中占很大比例。猝死的危险因素是透析患者特有的,包括血液透析期间液体和电解质失衡,特别是钾的失衡。心律失常的发生可能与透析过程中血清K+浓度的变化有关,因此应密切关注透析液K+浓度和血清透析液浓度梯度。钾谱分析是一种透析液K+浓度逐渐降低以保持血液和透析液之间的梯度在一个不波动的低水平的技术。我们提供了比较透析液钾浓度恒定和透析液钾浓度逐渐降低的研究综述。这些研究表明,充分和更渐进的钾去除可以实现钾谱技术,同时具有较低的心脏烦躁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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