A Comparative Study on The Synergistic Effect of Different Remineralizing Topical Agents And Biofilm Modifiers on Enamel Demineralization Around Orthodontic Brackets: An In Vivo Study

Abstract

Aim: To evaluate and compare the remineralizing potential of the two remineralizing topical agents (TCP, MI PAST PLUS) with and without xylitol. Subjects and Methods : This study was conducted on twenty patients five in each group. Group1. The teeth were treated by clinpro white varnish. Group2. The teeth were treated by MI Paste Plus™, Group3. The teeth were treated by clinpro white varnish with xylitol, and Group 4 where the teeth were treated by MI past plus with xylitol. The remineralizing effect was evaluated through photographic analysis of color changes using USB digital microscope at 0,3,6 and 9 months (T0, T1, T2 & T3). In addition, Micro hardness test and energy dispersive x-ray analysis were carried out on premolars obtained from patients indicating for therapeutic extraction for orthodontic treatment. Results: The present study revealed that: (1) For Vickers surface hardness. The highest mean values were recorded for Group 3. (2) For energy dispersive x-ray, the highest total enamel mineral profile contents were recorded for Group (3) For Color Change (ΔE) Assessment, at T1 as well as T2 the highest color changes were recorded for Group 2 and While at T3 the highest color changes were recorded for Group 1 Conclusion: The tooth pastes containing TCP has good effect on remineralization potential of the enamel in teeth and the addition of xylitol can enhance the potential effect of remineralizing topical agents. bonding (4) . The prevalence of WSLs after orthodontic treatment varies from 2% to 96% (5) . Enamel demineralization not only violates the esthetic principle of orthodontic treatment but also damages tooth health. Besides all the