Squamous Cell Bladder Cancer Associated with Large Bladder Stone: Literature Review and Its Case Report

S. Pramod, Ferry Safriadi, Rizqia Abyaksa
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Abstract

Bladder cancer is the most common urinary tract malignancy. Radical cystectomy is preferred as gold standard therapy for non-metastatic SCC, reflected from better survival rates than other treatment options such as partial cystectomy, chemotherapy, and radiation. Several factors are associated with the occurrence of bladder cancer, including bladder stone and infection ; such conditions suggestively could cause chronic irritation on the bladder surface epithelial, causing cancerous lesion to arise. Several literatures have showed positive outcome of patients with bladder cancer that underwent radical cystectomy. Thus, it is recommended to be performed on bladder cancer cases. Hereby we present a case of a 50-years old male who underwent radical cystectomy and bilateral ureterocutaneoustomy after previous trans urethral resection of bladder tumor (TURB-T) due to squamous cell bladder cancer. At the time of admission, he had bladder stone that based on imaging result, has already penetrated adjacent tissues. We also conducted literature review to assess our case with the other reports regarding the outcome of radical cystectomy for bladder SCC.
鳞状细胞膀胱癌合并大膀胱结石:文献回顾及病例报告
膀胱癌是泌尿系统最常见的恶性肿瘤。根治性膀胱切除术是治疗非转移性鳞状细胞癌的金标准,其生存率高于其他治疗方案,如部分膀胱切除术、化疗和放疗。几个因素与膀胱癌的发生有关,包括膀胱结石和感染;这种情况可能引起膀胱表面上皮的慢性刺激,导致癌变。一些文献显示膀胱癌患者行根治性膀胱切除术后预后良好。因此,建议在膀胱癌病例中进行。我们在此报告一位50岁男性病患,因鳞状细胞膀胱癌而行经尿道膀胱肿瘤切除术(TURB-T)后,行根治性膀胱切除术及双侧输尿管膀胱造口术。入院时,他患有膀胱结石,根据影像学结果,膀胱结石已经渗透到邻近组织。我们还进行了文献回顾,以评估我们的病例与其他报道有关膀胱SCC根治性膀胱切除术的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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