STUDY THE EFFECT OF ETHANOLIC EXTRACT OF CERATOINA SILIQUA, GLIMEPHAN AND METFORMIN ON SEMEN FLUID QUALITY IN DIABETIC MALE GUINEA PIG INDUCED BY ALLOXAN

Abstract

This study was carried out in an animal house of the Collage of Veterinary Medicine/ University of Basrah, An attempt has been done to induce diabetic by alloxan in male guinea pigs and investigation of the effects of diabetic on semen fluid quality. Moreover, the present study aimed to evaluate the ameliorating effect of ethanolic extract of Ceratonia siliqua , metformin and Glimphan in experimentally induced in diabetic male guinea pigs. The study was applied on (30) adult male guinea pigs, their weight ranged between (800-1000g) and aged between 6-6.5 months. The male guinea pigs were divided randomly into five groups, each group consist of six guinea pig as the following: performance of male reproductive system as compared with other treated such as glimephan and metformin drugs. The results indicated significant and testosterone in serum and semen diabetic male (+ve) as compared with the control negative group and other groups while the results showed non-significant (P˃0.05) changes of FSH and LH concentrations in serum of diabetic male pigs treated with ethanolic extract of Ceratonia siliqua fruit as compared with control (-ve) group while the results were showed a significant(P≤0.05) rise of testosterone serum and semen diabetic male of Ceratonia siliqua fruit whencompared with the control (–ve) group and other groups.