Applying Principle Component Analysis for Detecting Skin Damage Caused by Using Detergents: A Raman Spectroscopy Study

Abstract

In this paper, we study the alterations in skin molecular structures bond vibrations due to contact with chemical detergents. The main goal of this study was to investigate the damage a chemical detergent may have on skin structures and to determine the main vulnerable part of the skin. In our approach, we use micro Raman Spectroscopy on chicken skin samples in situ and benefit from the Principle Component Analysis to automatically discriminate the normal and the damaged skin in different spectral regions associated with different structures of skin. Results suggest that this method can be useful for detecting the damaged part of the skin in an animal model.