Oxidative Transformation of Mandelic acid by Pyridiniumdichromate in non-aqueous medium kinetic and mechanistic study

Abstract

The alpha–hydroxy acids (AHA) are naturally occurring organic acid. The oxidation of mandelic acid by pyridiniumdichromate has been studied spectrophotometrically in presence of p-toluenesulphonic acid (PTSA) in dimethylsulphoxide (DMSO) as a solvent. The rate of reaction decrease & with an increase in polarity of solvent indicating an ion-dipole interaction in the slow step. The reaction exhibit no primary kinetic isotope effect. The activation parameters have been evaluated.