Multiple non-familial trichoepitheliomas: A rare case and a review of the literature

Abstract

Trichoepitheliomas are benign tumors of follicular origin often appearing in childhood or early adolescence. They present as small, firm papulonodular lesions of normal skin color or translucent. The lesions gradually increase in size and then stabilize. They sit electively on the face, mainly on the nasolabial folds, forehead, chin, and cheeks, and sometimes on the scalp and neck. Trichoepitheliomas may be divided into three subgroups: multiple familial trichoepitheliomas, solitary non-hereditary trichoepitheliomas, and desmoplastic trichoepitheliomas. Non-familial multiple trichoepitheliomas are rarely described. Herein, we report the case of a twelve-year-old child whose clinical history and clinicopathologic correlation allowed us to retain the diagnosis of multiple non-familial trichoepitheliomas. Key words: Trichoepitheliomas; Sporadic; Genodermatosis; Cyld Gene; Anatomopathology