A cross-sectional study of lipid profile in anemic patients in a tertiary care center

Sruthisri Beeravelli, Nagarajan Kinathankaraiyan, Rajendran Manickam
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Abstract

Background: Various studies have reported a correlation (both positive and negative) between the status of anemia and lipid profile. Studies observed that the lipoproteins levels were significantly lower in anemic patients, and this reduction was proportional to the severity of anemia and not related to the type of anemia. Objectives: To study the lipid profile among the anemia patients and the correlation between the severity of the anemia and lipid subfractions. Materials and Methods: This is a cross-sectional study among 85 subjects with anemia in a Tertiary care hospital, who satisfied the eligibility criteria. After detailed history, clinical examination and blood investigations including blood counts, hemoglobin, and lipid profile were done. Results: The mean hemoglobin (g/dL) among the subjects was 7.86 (±2.03) g/dL ranging from 3 to 11 g/dL. Among the 85 subjects, 35 (41.18%) had dimorphic anemia followed by 21 (24.71%) had microcytic hypochromic anemia, 15 (17.65%) had normocytic hypochromic anemia, and 14 subjects (16.47%) had normocytic normochromic anemia. Body mass index was not significantly associated with the type and severity of anemia. Lipid subfractions were not associated with the type of anemia and significantly decreased with an increase in the severity of anemia. Conclusion: The lipid profile parameters in our study were not associated with type of anemia and significantly decreased with an increase in the severity of anemia.
三级保健中心贫血患者血脂剖面的横断面研究
背景:各种研究已经报道了贫血状态和血脂之间的相关性(包括正相关性和负相关性)。研究发现,贫血患者的脂蛋白水平明显降低,这种降低与贫血的严重程度成正比,而与贫血的类型无关。目的:研究贫血患者血脂状况及贫血严重程度与血脂亚组分的关系。材料和方法:这是一项横断面研究,纳入三级医院85例贫血患者,符合入选标准。经过详细的病史、临床检查和血液调查,包括血细胞计数、血红蛋白和血脂。结果:受试者平均血红蛋白(g/dL)为7.86(±2.03)g/dL,范围为3 ~ 11 g/dL。85例患者中,二形型贫血35例(41.18%),小细胞型低色性贫血21例(24.71%),正型型低色性贫血15例(17.65%),正型型贫血14例(16.47%)。体重指数与贫血的类型和严重程度无显著相关性。脂质亚组分与贫血类型无关,并随着贫血严重程度的增加而显著降低。结论:本研究中血脂参数与贫血类型无关,且随着贫血严重程度的增加而显著降低。
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