MRI Template and Atlas Toolbox for the C57BL/6J Mouse Brain

Abstract

In order to compare brain-imaging measurements from different subjects, brain-mapping algorithms are commonly used to register individual brain onto a standardized brain atlas. In this study, SPM99 was used to linearly and nonlinearly coregister a spatially standardized T2-weighted template of C57BL/6J to the atlas by Paxinos and Franklin (2001), local accuracy of between atlas and template was evaluated, and a toolbox was developed. This study provides a foundation for the region of interest analysis for mouse brain images